FANDOM


Expression Atlas Edit

The European Bioinformatics Institute (apart of the European Molecular Biology Lab) provides the data associated with real life science experiments since the database started as the first Nucleotide Sequence Data Library online.

Background Edit

Established in 1980 at the European Molecular Biology Laboratory in Heidelberg, Germany, to serve as a database for sequences rather than having scientists submit them into journals. In 1992, the EMBL council voted to establish & move the headquarters to the Wellcome Trust Genome Campus in Hinxton, UK where it would be in closer proximity with the major sequencing efforts at the Wellcome Trust Sanger Institute.

About the Expression Atlas Edit

Run by the EBI/EMBL, the expression atlas is an online database dedicated to providing information on gene expression patterns under different biological conditions such as a gene knock-out, a plant treated with a compound, or in a particular organism part or cell.

ExpressionAtlas

Expression atlas search engine.

Baseline AtlasEdit

Baseline Atlas

Gene set from Baseline Atlas searches.

One of the two components of the Expression Atlas, the Baseline Atlas serves as the display for genetic information under "normal" conditions. This portion of the database could answer questions such as

"What genes are being expressed in the spleen?"

"What is the expression pattern for gene-X in normal tissue?"

Differential Atlas Edit

The second component of the Expression Atlas is called the "Differential Atlas". This allows users to see what genes are being up and down regulated throughout different environmental conditions, such as temperature conditions, yeast mutants.

Searching with Contrast

You can also search genes and contrast them with others.

Enhanced Searches Edit

The enhanced search options give you a number of preset sample attributes and experimental conditions that you can search along with for any specific gene expression.

References Edit

The European Bioinformatics Institute/ European Molecular Biology Laboratory database.

The Expression Atlas homepage.